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Great news for kids: OSSIOfiber® Metal-Free Compression Screws and Trimmable Fixation Nails are now FDA cleared for various bone fractures in children (ages 2-12) and adolescents (ages 12-21). Read More

OSSIOfiber® Compression

Don’t Just Fix It… Heal It — Naturally.

Bio-Integrative OSSIOfiber® Compression Screw and Sterile, Disposable Instrumentation

Superior Fixation meets Better Bone Healing. The Patient Experience is Yours to Transform.

Our Compression Screws deliver superior performance to conventional metal screws*,** and gradually integrate fully into bone, for a true return to full strength and a total healing that other implants simply can’t provide.

* In Vitro Initial Compression Strength Test. Data on File at OSSIO.
** In Vitro Pull-Out Strength Test of 3.5x26mm OSSIOfiber Compression Screws. Data on File at OSSIO.

Performance Data:




Ordering Info

Bio-Integrative OSSIOfiber® Compression Screws

  • Comprised of OSSIOfiber® Intelligent Bone Regeneration Technology
  • Up to 5X increased surface area available for bone integration may contribute to a more stable construct4
  • Artifact free on CT, X-Ray. MRI safe

Choose the size and orientation that best fits your patients’ needs:

  • 3.5mm diameter with 12 – 32mm lengths in 2mm increments
  • 4.0mm diameter with 26 – 60mm lengths in 2mm increments
Product Bottom Ossio – Naturally Transformative Bone Healing

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For Product Inquiries, Customer Service, Ordering Information…
Contact Us At:

(833) 781-7373 |

Surgical Technique for the OSSIOfiber® Compression Screw

Superior Fixation with Familiar, Reproducible Technique

Achieve Natural Bone Healing without Tradeoffs on Performance or Trusted Technique

  • Pre-sterilized, single-use packaging with convenient disposable instruments to reduce unnecessary exposure to pathogens
  • Streamlined, cannulated instrumentation
Download Surgical Technique Guide
Google Docs 1 Ossio – Naturally Transformative Bone Healing
Ossio Compressionscrews Steps Ossio – Naturally Transformative Bone Healing

For illustration purposes only

Ossiofiber Final Callouts 1 Scaled 1 Ossio – Naturally Transformative Bone Healing

The Science Behind OSSIOfiber® Intelligent Bone Regeneration Technology

A True Breakthrough in Orthopedic Fixation

As a first-of-its-kind implant material, OSSIOfiber® is stronger than cortical bone and leaves nothing permanent behind. It leverages the individual integration mechanism of both material components and internal micro-architecture to achieve the optimal environment for bone healing.

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Frequently Asked Questions (FAQ)

The OSSIOfiber® Compression Screws are indicated for maintenance of alignment and fixation of bone fractures, comminuted fractures, fragments, osteotomies, arthrodesis, and bone grafts, of the upper extremity, fibula, knee, ankle and foot in the presence of appropriate brace and/or immobilization.

Strong and bio-integrative OSSIOfiber Compression screws can be chosen in lieu of standalone conventional, metal compression screws. Refer to the product Instructions for Use for indications, contraindications, and additional information. 

Yes, the OSSIOfiber® Compression Screw is covered under existing reimbursement codes in the US for common orthopedic procedures. Please contact OSSIO for more information.

OSSIOfiber® is the first and only Bio-Integrative Implant Technology. It is 5x stronger than conventional bio-resorbables and uniquely contributes to early bone attachment and subsequent bone integration. Findings from a 2-year preclinical study comparing OSSIOfiber® to bio-resorbables showed that unlike bio-resorbables, OSSIOfiber® integrates in a gradual and predictable way, with no adverse inflammation observed. Please refer to the “Science Behind OSSIOfiber®” page of this website for more detailed information. *Data on file at OSSIO

The OSSIOfiber® bio-integration process begins shortly after surgery and continues in a gentle, gradual, and predictable way until it is completely incorporated into the surrounding anatomy in roughly 78-104 weeks, as proven in pre-clinical studies. After full bio-integration, the implant is completely gone and replaced by healthy bone. Bone attachment is seen in as little as 2 weeks post surgery, followed by incorporation and ultimate replacement of the implant by tissue – a process that continues until nothing permanent is left behind.

OSSIOfiber® is currently commercially available in the US. If you are interested in using OSSIOfiber®, please fill out the form below and a team member will be in touch.

Interested in OSSIOfiber®?

Complete the form and an OSSIOfiber® Advisor will get in touch.

Customer Service

For product inquiries or purchasing questions contact 833-781-7373 or email


Commercial Headquarters
300 Tradecenter Drive, Suite 3690
Woburn, MA, 01801

Science & Manufacturing Center

8 HaTochen Street
Cesarea, Israel 3079861

OSSIOfiber® has been used by over 900 surgeons across the US


1. Data on file at OSSIO 2. Clinical study data on file at OSSIO 3. Kaiser, P.B., Watkins, I., Riedel, M. D., Cronin, P., Briceno, J., Kron, J. Y. (2019). Implant Removal Matrix for the Foot and Ankle Orthopaedic Surgeon. Foot & Ankle Specialist, 12(1), 79-97. 4. Pre-clinical animal studies (in-bone implantation of OSSIOfiber® and PLDLA control in rabbit femurs). Data on File at OSSIO. 5.Haddad, S. F., Helm, M. M., Meath, B., Adams, C., Packianathan, N., & Uhl, R. (2019). Exploring the Incidence, Implications, and Relevance of Metal Allergy to Orthopaedic Surgeons. Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 3(4), e023.