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Great news for kids: OSSIOfiber® Metal-Free Compression Screws and Trimmable Fixation Nails are now FDA cleared for various bone fractures in children (ages 2-12) and adolescents (ages 12-21). Read More

OSSIOfiber® Compression Staple

Evolve to Stronger, Bio-Integrative Compression

Staple Padded Ossio – Naturally Transformative Bone Healing

Bio-Integrative OSSIOfiber® Compression Staple

Fix the Bone, Nix the Nitinol

OSSIOfiber® Compression Staples provided greater compressive force versus other widely used nitinol staples.1,*

Squeeze Ossio – Naturally Transformative Bone Healing

OSSIOfiber® Compression Staples provided greater compressive force versus other widely used nitinol staples.1,*

Gap Ossio – Naturally Transformative Bone Healing

OSSIOfiber® Compression Staples provide increased resistance to plantar gapping vs nitinol staples.1,*


Fatigue strength tested to over 1 million cycles to ensure reliable strength over time

* Tested using 15×15 mm staples.




Ordering Info

Bio-Integrative OSSIOfiber® Compression Staple

  • Avoid Hardware Removal Procedures – Leave nothing permanent behind with bio-integrative OSSIOfiber®
  • See the Fusion, Not the Implant – See healing bone without the obstruction of a metal implant
  • Customize Your Implant Construct – The ONLY trimmable bone staple that allows for customizable leg lengths
  • Only Nature Remains – Reliable and safe bio-integration of the entire implant within 24 months
  • Nickel-Free, Worry Free – Provide a nickel-free solution to metal sensitive patients

Choose configuration that best fits your patients’ needs:

  • 9 x 10 mm
  • 11 x 10 mm
  • 15 x 15 mm
  • 20 x 20 mm
  • 25 x 22 mm
Ossio 22 2 Ossio – Naturally Transformative Bone Healing
1 Product Bottom Ossio – Naturally Transformative Bone Healing

Want to Order? Hear More?

For Product Inquiries, Customer Service, Ordering Information…
Contact Us At:

(833) 781-7373 |

An Architecture for Strength

The shoulders and bridge of each OSSIOfiber® Compression Staple are engineered with an increased allocation of mineral fibers providing reliable strength where it’s needed most.

Superior Compression Delivered

Thousands of natural mineral fibers work together to actively compress
the fusion site, delivering superior compression vs nitinol1.

Intelligent Bone Regeneration

OSSIOfiber®’s matrix of interconnected pores allow for bone in-growth and complete bio-integration in 24 months with no adverse inflammation1.

Disposable Instrumentation System
9, and 11 mm

For illustration purposes only

Surgical Technique Guide
Google Docs 1 Ossio – Naturally Transformative Bone Healing
See Product Animation Video Play Button 3 Ossio – Naturally Transformative Bone Healing

Disposable Instrumentation System
15, 20, and 25 mm

For illustration purposes only

Surgical Technique Guide
Google Docs 1 Ossio – Naturally Transformative Bone Healing
See Product Animation Video Play Button 3 Ossio – Naturally Transformative Bone Healing

Ossiofiber Final Callouts 1 Scaled 1 Ossio – Naturally Transformative Bone Healing

The Science Behind OSSIOfiber® Intelligent Bone Regeneration Technology

A True Breakthrough in Orthopedic Fixation

As a first-of-its-kind implant material, OSSIOfiber® is stronger than cortical bone and leaves nothing permanent behind. It leverages the individual integration mechanism of both material components and internal micro-architecture to achieve the optimal environment for bone healing.

Learn More

Frequently Asked Questions (FAQ)

Yes, the OSSIOfiber® Compression Staple is covered under existing reimbursement codes in the US for common orthopedic procedures. Please contact OSSIO for more information.

OSSIOfiber® is the first and only Bio-Integrative Implant Technology. It is 5x stronger than conventional bio-resorbables and uniquely contributes to early bone attachment and subsequent bone integration. Findings from a 2-year preclinical study comparing OSSIOfiber® to bio-resorbables showed that unlike bio-resorbables, OSSIOfiber® integrates in a gradual and predictable way, with no adverse inflammation observed. Please refer to the “Science Behind OSSIOfiber®” page of this website for more detailed information. *Data on file at OSSIO

The OSSIOfiber® bio-integration process begins shortly after surgery and continues in a gentle, gradual, and predictable way until it is completely incorporated into the surrounding anatomy in roughly 78-104 weeks, as proven in pre-clinical studies. After full bio-integration, the implant is completely gone and replaced by healthy bone. Bone attachment is seen in as little as 2 weeks post surgery, followed by incorporation and ultimate replacement of the implant by tissue – a process that continues until nothing permanent is left behind.

OSSIOfiber® is currently commercially available in the US. If you are interested in using our products, please fill out the form below and a team member will be in touch.

Interested in OSSIOfiber®?

Complete the form and an OSSIOfiber® Advisor will get in touch.

Customer Service

For product inquiries or purchasing questions contact 833-781-7373 or email


Commercial Headquarters
300 Tradecenter Drive, Suite 3690
Woburn, MA, 01801

Science & Manufacturing Center

8 HaTochen Street
Cesarea, Israel 3079861

OSSIOfiber® has been used by over 900 surgeons across the US


1. Data on file at OSSIO 2. Clinical study data on file at OSSIO 3. Kaiser, P.B., Watkins, I., Riedel, M. D., Cronin, P., Briceno, J., Kron, J. Y. (2019). Implant Removal Matrix for the Foot and Ankle Orthopaedic Surgeon. Foot & Ankle Specialist, 12(1), 79-97. 4. Pre-clinical animal studies (in-bone implantation of OSSIOfiber® and PLDLA control in rabbit femurs). Data on File at OSSIO. 5.Haddad, S. F., Helm, M. M., Meath, B., Adams, C., Packianathan, N., & Uhl, R. (2019). Exploring the Incidence, Implications, and Relevance of Metal Allergy to Orthopaedic Surgeons. Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 3(4), e023.